Von Willebrand's Disease (***)

The most common hereditary coagulation abnormality characterized by a qualitative or quantitative deficiency of von Willebrand’s factor (vWF).

vWF is Factor VIII

Type I – mild decrease in vWF Type II – qualitative vWF defect, with normal levels Type III – most severe (homozygous) form with very low levels of vWF

Give cryoprecipitate (~ 10 units) and DDAVP with bypass termination.

Pa tients will need to be monitored closely postoperatively for excessive bleeding

DDAVP = DESMOPRESSIN